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Increased blood BACE1 activity as a potential common pathogenic factor of vascular dementia and late onset Alzheimer's disease

Nature
Late onset Alzheimer disease (LOAD) is traditionally considered as a separate disease from vascular dementia (VAD).
50 bulan yang lalu

Circulating microRNAs as biomarkers for stratifying different phases of liver cancer progression and response to therapy

Nature
Hepatocellular carcinoma (HCC) is the most common liver cancer and is among the leading causes of cancer-related death worldwide.
3 bulan yang lalu

Cholesterol efflux capacity is increased in subjects with familial hypercholesterolemia in a retrospective case–control study

Nature
Familial Hypercholesterolemia (FH) is characterized by an increase in Low-Density Lipoprotein Cholesterol (LDL-C) and by premature...
18 bulan yang lalu

Spiropiperidine-Based Oligomycin-Analog Ligands To Counteract the Ischemia–Reperfusion Injury in a Renal Cell Model | Journal of Medicinal Chemistry

ACS Publications
We applied a combination of molecular modeling and chemical synthesis to identify novel spiropiperidine-based structures active in mitochondrial permeability...
12 bulan yang lalu

HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts

Nature
Our findings suggest that snail mucus biological effects are attributable to cell proliferation and migration, and pave the way for further investigating snail...
72 bulan yang lalu

A thorough annotation of the krill transcriptome offers new insights for the study of physiological processes

Nature
The krill species Euphausia superba plays a critical role in the food chain of the Antarctic ecosystem. Significant changes in climate...
28 bulan yang lalu

Influence of the Generator in-Growth Time on the Final Radiochemical Purity and Stability of

Wiley Online Library
The aim of this work was to evaluate the possible impact of different 99g Tc/ 99m Tc isomeric ratios on the preparation of different Tc-labeled pharmaceutical...
134 bulan yang lalu

Improved Hole Extraction and Band Alignment via Interface Modification in Hole Transport Material-Free Ag/Bi Double Perovskite Solar Cells

Wiley Online Library
Within one decade, lead halide perovskite solar cells have reached power conversion efficiencies (PCEs) compatible with that of silicon...
10 bulan yang lalu

Self-Sustaining Cleaning Technology for Safe Water Supply and Management in Rural African Areas

CORDIS | European Commission
This project focuses on a major challenge in African countries: In the 15 sub-Saharan African countries 108 million people have limited or...
27 bulan yang lalu

Lotta contro l'AIDS | Grande adesione al presidio Unife per test HIV gratuiti e anonimi

Università degli studi di Ferrara
Grande adesione di studentesse e studenti dell'Università di Ferrara giovedì 24 febbraio nella Sala studio acquario del Polo Chimico Bio...
33 bulan yang lalu