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Circulating microRNAs as biomarkers for stratifying different phases of liver cancer progression and response to therapy

Nature
Hepatocellular carcinoma (HCC) is the most common liver cancer and is among the leading causes of cancer-related death worldwide.
3 bulan yang lalu

Cholesterol efflux capacity is increased in subjects with familial hypercholesterolemia in a retrospective case–control study

Nature
Familial Hypercholesterolemia (FH) is characterized by an increase in Low-Density Lipoprotein Cholesterol (LDL-C) and by premature...
18 bulan yang lalu

Increased blood BACE1 activity as a potential common pathogenic factor of vascular dementia and late onset Alzheimer's disease

Nature
Late onset Alzheimer disease (LOAD) is traditionally considered as a separate disease from vascular dementia (VAD).
50 bulan yang lalu

Spiropiperidine-Based Oligomycin-Analog Ligands To Counteract the Ischemia–Reperfusion Injury in a Renal Cell Model | Journal of Medicinal Chemistry

ACS Publications
We applied a combination of molecular modeling and chemical synthesis to identify novel spiropiperidine-based structures active in mitochondrial permeability...
12 bulan yang lalu

Bubbles enable volumetric negative compressibility in metastable elastocapillary systems

Nature
Although coveted in applications, few materials expand when subject to compression or contract under decompression, i.e., exhibit negative...
5 bulan yang lalu

A thorough annotation of the krill transcriptome offers new insights for the study of physiological processes

Nature
The krill species Euphausia superba plays a critical role in the food chain of the Antarctic ecosystem. Significant changes in climate...
28 bulan yang lalu

Improved Hole Extraction and Band Alignment via Interface Modification in Hole Transport Material-Free Ag/Bi Double Perovskite Solar Cells

Wiley Online Library
Within one decade, lead halide perovskite solar cells have reached power conversion efficiencies (PCEs) compatible with that of silicon...
10 bulan yang lalu

HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts

Nature
Our findings suggest that snail mucus biological effects are attributable to cell proliferation and migration, and pave the way for further investigating snail...
71 bulan yang lalu

Kinetics and energetics of metal halide perovskite conversion reactions at the nanoscale | Communications Materials

Nature
We find that kinetics and grain orientation strongly depend on both the lead halide framework and the nature of the A-cation, with fastest kinetics for MAPbI 3.
31 bulan yang lalu

Influence of the Generator in-Growth Time on the Final Radiochemical Purity and Stability of

Wiley Online Library
The aim of this work was to evaluate the possible impact of different 99g Tc/ 99m Tc isomeric ratios on the preparation of different Tc-labeled pharmaceutical...
134 bulan yang lalu