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Gβ promotes pheromone receptor polarization and yeast chemotropism by inhibiting receptor phosphorylation
Science | AAAS
Gradient-directed cell migration (chemotaxis) and growth (chemotropism) are processes that are essential to the development and life cycles...
103 bulan yang lalu
Mutations in Hirschsprung Disease: When Does a Mutation Contribute to the Phenotype
Nature
Hirschsprung disease is a congenital disorder clinically characterized by the absence of colonic ganglia and genetically by extensive heterogeneity.
66 bulan yang lalu
Genetic insights, disease mechanisms, and biological therapeutics for Waardenburg syndrome
Nature
Waardenburg syndrome (WS), also known as auditory-pigmentary syndrome, is the most common cause of syndromic hearing loss (HL),...
45 bulan yang lalu
Progress of Catalytic Valorization of Bio-Glycerol with Urea into Glycerol Carbonate as a Monomer for Polymeric Materials
Wiley Online Library
In this review, recent studies on GC synthesis involving the catalysts such as zinc, magnesium, tungsten, ionic liquid-based catalysts, reaction conditions,...
58 bulan yang lalu
What is new about the genetic background of Hirschsprung disease? - Luzón‐Toro - 2020 - Clinical Genetics
Wiley Online Library
Hirschsprung disease (HSCR) is a rare congenital disorder caused by an incorrect enteric nervous system development due to a failure in...
64 bulan yang lalu
Mowat–Wilson syndrome: Facial phenotype changing with age: Study of 19 Italian patients and review of the literature
Wiley Online Library
Mowat–Wilson syndrome (MWS; OMIM #235730) is a genetic condition caused by heterozygous mutations or deletions of the ZEB2 gene,...
189 bulan yang lalu
Promoter methylation and transgene copy numbers predict unstable protein production in recombinant chinese hamster ovary cell lines
Wiley Online Library
Abstract Mammalian cell lines for recombinant protein production need to maintain productivity over extended cultivation times.
162 bulan yang lalu
Differential DNA methylation patterns of small B-cell lymphoma subclasses with different clinical behavior
Nature
Non-Hodgkin's lymphoma (NHL) is a group of malignancies of the immune system with variable clinical behaviors and diverse molecular features...
219 bulan yang lalu
Growth delay of human pancreatic cancer cells by methylase inhibitor 5-aza-2′-deoxycytidine treatment is associated with activation of the interferon signalling pathway
Nature
Alteration of methylation status has been recognized as a possible epigenetic mechanism of selection during tumorigenesis in pancreatic...
238 bulan yang lalu
Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancers | Oncogene
Nature
These 3p genetic alterations lead to the conclusion that the short arm of human chromosome 3 contains several tumor suppressor gene(s) (TSG(s)).
265 bulan yang lalu